celox-coated gauze for the treatment of civilian penetrating trauma: a randomized clinical trial

conclusions using the celox-coated gauze is able to achieve hemostasis in penetrating limb trauma faster than the conventional pressure bandage. further research is required to clarify the subset of patients who will benefit the most from this effect in the emergency department. results the mean age of participants was 30.5 and the majority of patients were male (90.6%). the forearm and distal leg were the most sites of injury. hemostasis was achieved within 5 minutes in 32.5% of the control group and 51.3% of the intervention group. using the celox-coated gauze significantly reduced the time to hemostasis (p = 0.01). moreover, the blood loss was significantly lower in the celox group compared to the controls (p < 0.05). patients and methods in this clinical trial study, 160 patients with penetrating limb trauma were randomly allocated to either the control or intervention group (n = 80, each group). controls were treated with the simple pressure dressing, while the celox-coated gauze was used in the intervention group. the time for achievement of hemostasis and the amount of bleeding were recorded. data were analyzed using spss version 21 and stata 13. a p value of less than 0.05 was considered statistically significant. background uncontrolled hemorrhage is a well-recognized cause of mortality in trauma victims and the control of active hemorrhage is among the initial steps in resuscitation. objectives the purpose of this study was to assess the role of a hemostatic agent “celox” in the management of civilian stab-wound trauma.